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Each uncoated tablet contains Mefloquine Hydrochloride equivalent to Mefloquine 250 mg.
Mefliam is for use as a second line treatment in chloroquine resistant malaria, severe malaria due to P. falciparum and P. vivax including cerebral malaria.
Not to be used as a first line treatment for malaria.
Mefliam should be taken with plenty of water and preferably with food.
The dosage depends on the immune status and body weight of the patient.
Adults 15-25 mg per kg body weight.
1250 to 1500 mg/day as a single dose or in two or three divided doses six to eight hours apart.
750 to 1000 mg/day as a single dose.
For better tolerance, adult doses over 750 mg (3 tablets) should be divided, giving 3 tablets first and the rest after 6-8 hours.
25 mg/kg body weight
In case of life threatening, serious or overwhelming malaria infection due to P. falciparum patients should be treated with an intravenous anti-malarial drug.
Following completion of intravenous treatment, Mefliam may be given orally to complete the course of therapy.
Mefliam is contraindicated if you have any of the following conditions:
- Hypersensitivity to mefloquine or related compounds (eg. Quinine);
- A history of seizure or psychiatric illness.
- Strip of 6 Tablets;